TGF-beta/Smad
PTEN
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Product name : BEZ235 (NVP-BEZ235, Dactolisib)
Product No. : cc
Price : 100mg/$375, 500mg/$475
CAS :
Bulk inquiry :
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| Details: |
NMRBEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM/5 nM/7 nM/75 nM/6 nM, respectively; inhibits ATR with IC50 of 21 nM; shown to be poor inhibitory to Akt and PDK1.
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