Product name : ND-630 (NDI-010976, GS-0976)
Product No. : cs-2599
Price : 50mg, $975; 100mg/$1475
CAS :
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ND-630 (CAS: 1434635-54-7) is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively. ND-630 nteracts within the ACC phosphopeptide acceptor and dimerization site to prevent dimerization and inhibit the enzymatic activity of both ACC isozymes, reduce fatty acid synthesis and stimulate fatty acid oxidation in cultured cells and in animals, and exhibit favorable drug-like properties. |
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