TGF-beta/Smad
Phospholipase
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Product name : Azeliragon (TTP488, TTP-488)
Product No. : cs-2071
Price : 50mg, $675; 100mg, $1175
CAS :
Bulk inquiry :
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| Details: |
TTP 488 (CAS: 603148-36-3) is a potent and orally active RAGE inhibitor. RAGE (receptor for advanced glycation endproducts) is a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's-associated protein, into the brain. In preclinical studies, azeliragon decreased brain amyloid in mice and improved their performance on behavior tests. Azeliragon is a promising agent for for Alzheimer's disease and cerebral amyloid angiopathy.
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