TGF-beta/Smad
Phospholipase
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Product name : Bindarit (AF-2838, AF2838)
Product No. : cs-1989
Price : 100mg, $675, 500mg/$1875
CAS :
Bulk inquiry :
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| Details: |
AF 2838 (CAS: 130641-38-2), a CCL2, CCL7 and CCL8 inhibitor, is an anti-inflammatory agent. Bindarit protects against bone loss induced by chikungunya virus infection. Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching. Bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis. Bindarit prolongs survival and reduces renal damage in NZB/W lupus mice.
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