TGF-beta/Smad
Nampt
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Product name : NVP-BEP800(VER82576, VER-82576)
Product No. : cs-1973
Price : 100mg, $475, 500mg/$1275
CAS :
Bulk inquiry :
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| Details: |
NVP-BEP800 (CAS: 847559-80-2) is a novel, fully synthetic, oral Hsp90 inhibitor with an IC50 of 0.058 ± 0.006 μM. NVP-BEP800 showed activity against a panel of human tumor cell lines and primary human xenografts in vitro at nanomolar concentrations. In A375 melanoma and BT-474 breast cancer cell lines, NVP-BEP800 induced client protein degradation (including ErbB2, B-Raf(V600E), Raf-1, and Akt) and Hsp70 induction.
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