Products > Cell Cycle/DNA Damage > BET bromodomain > I-BET151( I-BET-151, GSK1210151A, GSK1210151A, GSK 1210151A)
Product name : I-BET151( I-BET-151, GSK1210151A, GSK1210151A, GSK 1210151A)
Product No. : cs-1920
Price : 100mg, $475, 500mg/$1275
CAS :
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I BET151(CAS: 1300031-49-5) is a BET bromodomain inhibitor(pIC50=6.1,BRD4); I-BET151 blocks recruitment of BET to chromatin . I-BET151 ( GSK1210151A ) shows good oral bioavailability in both the rat and minipig as well as demonstrating efficient suppression of bacterial induced inflammation and sepsis in a murine in vivo endotoxaemia model.
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