Product name : HBX-41108 (HBX41108)
Product No. : cs-1900
Price : 100mg, $675, 500mg/$1875
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HBX 41108 (CAS: 924296-39-9) is inhibitor of ubiquitin-specific protease (USP) 7 activity (IC50 = 424 nM). HBX 41108 displays uncompetitive inhibition. Also inhibits USP7-mediated p53 deubiquitination (IC50 = 0.8 μM). Stabilizes p53 and inhibits cancer cell growth; induces p53-dependent apoptosis in p53 wild type and null isogenic cancer cell lines.
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