TGF-beta/Smad
VEGFR
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Product name : DMH-1 (DMH1; DMH 1)
Product No. : cs-1204
Price : 100mg, $475, 500mg/$1275
CAS :
Bulk inquiry :
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| Details: |
DMH-1 (CAS: 1206711-16-1) is a potent and selective BMP inhibitor with IC50s of 27/107.9/<5 nM for ALK1/2/3 respectively; inactive on ALK5, BMPR2, AMPK and VEGFR2. In the surrounding tumor microenvironment, treatment with DMH1 altered fibroblasts, lymphatic vessels and macrophages to be less tumor promoting.
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