TGF-beta/Smad
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Products > Metabolic enzyme/Protease > Farnesyl Transferase (FTase) > Tipifarnib (IND 58359; R115777; IND-58359; IND58359; R-115777; R 115777)
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Product name : Tipifarnib (IND 58359; R115777; IND-58359; IND58359; R-115777; R 115777)
Product No. : cs-2330
Price : 100mg, $675, 500mg/$1875
CAS :
Bulk inquiry :
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| Details: |
Tipifarnib (CAS: 192185-72-1) is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM, and the anti-proliferative effects are most prominent in H-ras or N-ras mutant cells. It inhibits the Ras kinase in a post translational modification step before the kinase pathway becomes hyperactive.
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