TGF-beta/Smad
c-Met inhibitor
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Product name : JI-101 (JI-101, JI-101)
Product No. : cs-2268
Price : 100mg, $675, 500mg/$1875
CAS :
Bulk inquiry :
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| Details: |
JI-101 (CAS: 900573-88-8) is an orally active inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor beta (PDGFRb), and the ephrin B4 receptor B4 (EphB4) with potential antiangiogenic and antineoplastic activities. The receptor tyrosine kinases VEGFR2, PDGFRb and EphB4 may be overexpressed in a number of different cancer cell types and may play crucial roles in tumor angiogenesis.
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