TGF-beta/Smad
MNK
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Product name : RAF265 (CHIR-265; RAF 265; RAF-265; CHIR265)
Product No. : cs-1852
Price : 100mg, $475, 500mg/$1275
CAS :
Bulk inquiry :
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| Details: |
RAF265 (CAS: 405169-16-6) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM. Raf kinases are critical enzymes in the Ras/Raf/MEK/ERK signaling pathway and are frequently upregulated in neoplasms.
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