TGF-beta/Smad
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Products > PI3K/Akt/mTOR > mTOR > SAR 245409 ((Voxtalisib; XL765; SAR-245409; SAR245409; XL 765; XL-765)
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Product name : SAR 245409 ((Voxtalisib; XL765; SAR-245409; SAR245409; XL 765; XL-765)
Product No. : cs-1242
Price : 100mg, $675, 500mg/$1875
CAS :
Bulk inquiry :
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| Details: |
SAR245409 (CAS: 934493-76-2) is a potent and highly selective pan inhibitor of class I PI3Ks (α/β/γ/δ, IC50=39/110/9/43 nM) with activity against mTOR(IC50=160-910 nM). XL765 inhibits both PI3K kinase and mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in susceptible tumor cell populations.
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