TGF-beta/Smad
Bombesin Receptor
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Product name : EHT-1864 (EHT1864, EHT 1864)
Product No. : cs-1239
Price : 100mg, $875, 500mg/$2475
CAS :
Bulk inquiry :
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| Details: |
EHT-1864 (CAS: 754240-09-0) is a potent Rac family GTPase inhibitor with Kd of 40 nM, 50 nM, 60 nM and 250 nM for Rac1, Rac1b, Rac2 and Rac3, respectively. EHT 1864 attenuates glucose-stimulated insulin secretion in pancreatic β-cells. EHT 1864 specifically inhibits glucose-induced Rac1 activation and membrane association and associated downstream signaling events culminating in inhibition of GSIS.
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