TGF-beta/Smad
PTEN
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Product name : GSK2141795 (Uprosertib, GSK-2141795)
Product No. : cs-1302
Price : 100mg, $675, 500mg/$1475
CAS : cs-1302
Bulk inquiry : contact sales@cckinase.com for bulk inquiry
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GSK2141795 (CAS: 1047634-65-0) is a potent and selective pan-Akt inhibitor with IC50 values of 180 nM for Akt1, 328 nM for Akt2, and 38 nM for Akt3 respectively. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents.
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