TGF-beta/Smad
MNK
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Product name : TAK-580 (MLN-2480, BIIB024)
Product No. : cs-2188
Price : 100mg, $475, 500mg/$1275
CAS :
Bulk inquiry :
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| Details: |
TAK-580 (CAS: 1096708-71-2), also known as MLN2480, BIIB024, and AMG 2112819, is an oral, selective pan-Raf kinase inhibitor. The Raf kinases (A-Raf, B-Raf and C-Raf) are key regulators of cell proliferation and survival within the mitogen-activated protein kinase (MAPK) pathway. The MAPK pathway is frequently disregulated in human cancers, often via activating mutations of Ras or Raf.
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