TGF-beta/Smad
Phospholipase
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Product name : Firategrast (SB-683699, SB683699, SB 683699)
Product No. : cs-1588
Price : 100mg, $675, 500mg/$1875
CAS :
Bulk inquiry :
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| Details: |
Firategrast (CAS: 402567-16-2) is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS). This could decrease multiple sclerosis (MS) activity, but may compromise CNS immune surveillance. The integrins are a sort of transmembrane receptors that modulate the signal transduction from ECM to the cell. They are associated with a lot of diseases such as cancer, inflammation and thrombotic diseases.
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